This Week in PLOS

In PLOS Genetics, researchers from France describe a missense mutation in the KIF1C gene that appears to cause progressive ataxia in Charolais cattle in its homozygous form. The team used a bovine array to genotype 46 Charolais cattle that appeared to have the neurodegenerative condition.

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Microsoft co-founder Paul Allen also contributed to brain research, NPR reports.

The New York Times reports on the shifting interpretations of what some genetic variants mean over time.

In Cell this week: investigation of metastatic tumor evolution, more than 16,000 genetic variants introduced into the budding yeast model organism, and more.

MIT's Technology Review reports on Genentech's pursuit of personalized cancer vaccines.