This Week in PLOS

In PLOS Genetics, Colorado State University researchers report on results from a yeast genetic screen for sequences influencing yeast prion aggregation or degradation. Using randomly mutagenized yeast libraries missing the usual copy of a yeast prion protein called Sup35, the team searched for amino acid residues prompting the accumulation or breakdown of aggregation-prone, prion-like domain models from Sup35 and/or two human proteins.

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The New York Times and ProPublica say that many physicians fail to disclose their financial ties when publishing in medical journals.

The Wall Street Journal reports Human Longevity's valuation has dropped by 80 percent.

Science reports that the US National Cancer Institute is cutting its operating budget by 5 percent.

In PLOS this week: similar variants seen in bullbogs, people with Robinow syndrome; ApoE genotypes in African-American, Puerto Rican populations; and more.