This Week in PLOS

In PLOS Genetics, Colorado State University researchers report on results from a yeast genetic screen for sequences influencing yeast prion aggregation or degradation. Using randomly mutagenized yeast libraries missing the usual copy of a yeast prion protein called Sup35, the team searched for amino acid residues prompting the accumulation or breakdown of aggregation-prone, prion-like domain models from Sup35 and/or two human proteins.

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Researchers describe a way to share data while keeping it secure, Agence France Presse reports.

In Science this week: genetic mutations typically associated with esophageal cancer are common in older, healthy individuals, and more.

India's Council of Scientific and Industrial Research has a new director-general, according to ScienceInsider.

A new study links more than a hundred genes to autism spectrum disorder, Discover's D-brief blog reports.