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This Week in PLOS

In PLOS Genetics, researchers from Portugal describe their search for new genes associated with early onset or hereditary prostate cancer risk. The team did targeted sequencing on 94 suspected cancer genes in 121 individuals with prostate cancer, uncovering truncations and/or functionally deleterious mutations in two genes already implicated in prostate cancer and five new candidate genes.

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Researchers tie a variant in ADAMTS3 to breathing difficulties in dissimilar dog breeds, according to Discover's D-brief blog.

The Japan Times reports that researchers sequenced the genome of a woman who lived during the Jomon period.

Parents of children with rare genetic disease have to contend with shifts in the interpretation of genetic variants, the Wall Street Journal reports.

In Science this week: single-nucleus RNA sequencing of brain tissue from individuals with autism, and more.