This Week in PLOS

A University of California, Los Angeles-led team describes a hierarchical fine-mapping approach that brings together data at the genome, epigenome, and gene expression level. As they report in PLOS Genetics, the researchers' "pathfinder" fine-mapping framework is designed to account for both causal variants and chromatin marks that influence gene expression at sites of interest in the genome.

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A federal grand jury has indicted Elizabeth Holmes and Ramesh Balwani for alleged wire fraud in conjunction with their activities at Theranos.

Nature News reports that some developers are nervous about GitHub's acquisition by Microsoft.

A direct-to-consumer genetic testing company sent out used spit kits, CNBC reports.

In PLOS this week: comparison of commercial bisulfite kits, new method to predict essential proteins, and more