This Week in PLOS

Italian and American researchers, reporting in PLOS Pathogens, provide insights on a microRNA that appears to dissuade the immune system from performing autophagy in human dendritic cells infected with Mycobacterium tuberculosis. With array- and quantitative PCR-based analyses, the team followed miRNA expression at three, eight, and 24 hours after M. tuberculosis infection in dendritic cells, identifying dozens of differentially expressed miRNAs.

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Researchers hope to tease out the signature effects that different carcinogens leave on the genome to determine their contributions to disease, Mosaic reports.

The Wall Street Journal looks into the cost of new gene therapies.

An Imperial College London-led team reports that it was able to use a gene drive to control a population of lab mosquitos.

In PNAS this week: genomic effects of silver fox domestication, limited effect of mitochondrial mutations on aging in fruit flies, and more.