This Week in PLOS

In PLOS Genetics, a Columbia University-led team takes a look at a case-control gene-based collapsing approach for uncovering de novo mutations involved in epileptic encephalopathy. Focusing on very rare variants in protein-coding genes from 488 individuals with epileptic encephalopathy and 12,151 without, the researchers narrowed in on so-called qualifying variants that appeared to have pronounced effects on epileptic encephalopathy.

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An Australian-led team has generated a draft genome assembly of the invasive cane toad in hopes it will help in population control, the Sydney Morning Herald reports.

The New York Times reports that the US Department of Defense has implemented about half the recommendations made to improve safe handling of dangerous agents.

In PLOS this week: approach for teasing out archaic introgression in human genomes, immune transcription features in HCV infection, and more.

Stat News reports that Maryland is promoting itself to the biotech industry with a mobile billboard.