This Week in PLOS

In PLOS One, a team from Taiwan and Singapore explores the effectiveness of an 18-gene classifier for predicting distant metastasis in individuals with breast cancer. The researchers applied the algorithm — initially established to predict local progression or regional recurrence — to fresh-frozen primary breast tumor samples from 683 individuals with breast cancer, including 101 individuals who experienced metastasis and 583 who were metastases-free.

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Berkeley researchers have engineered yeast to make the molecule behind the hoppy taste of beer, Quartz reports.

King's College London researchers examine the influence of school type and genetics on academic achievement.

FiveThirtyEight writes that most who take a direct-to-consumer BRCA1/2 genetic test won't learn much from it.

In Science this week: early life experience influence somatic variation in the genome, and more.