This Week in PLOS

In PLOS Genetics, researchers from Yale University, Peking University, and the University of Washington report on findings from a study suggesting ties between immune-related DNA elements and susceptibility to late-onset Alzheimer's disease. The team began by using a statistical framework called GenoSkyline-Plus to narrow in on tissue-specific regulatory clues to complex conditions based on data from epigenetic and genome-wide association studies.

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Consulting company McKinsey says diagnostics companies will have to combine genomic data analysis, electronic medical records, effective reimbursement strategies, and regulatory compliance in order to win.

A new report has found that researchers in Africa are still heavily dependent on funding from organizations in the US, Europe, and China, Nature News says.

An article in The Atlantic argues that the progress being made in science isn't keeping pace with the money and time being spent on research.

In Science this week: a CRISPR screen identifies sideroflexin 1 as a requisite component of one-carbon metabolism, and more.