This Week in PLOS

In PLOS Genetics, researchers in Sweden, Germany, and Pakistan report on a role for an isoform of the claudin 10-coding gene CLDN10B in a rare genetic ­­­condition characterized by altered sweat glands, insufficient sweating, a lack of tears, poor heat tolerance, and related kidney damage.

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CNN reports that researchers have tied a new variant to opioid addiction risk.

Organoids derived from patients' tumors may help determine what chemotherapy treatment patients would benefit from, according to New Scientist.

An initiative from GenomeAsia 100K hopes to increase the number of South Asians in genetic research, according to NBC News.

In Science this week: genomic analysis of ancient and modern horses indicates population turnover, and more.