This Week in PLOS

For a study in PLOS Genetics, University of Toronto researchers consider potential ties between disease- or trait-related genetic variants and protein post-translational modification. Based on variant patterns in 7,500 human genomes, the team saw signs of negative selection involving regions of the genome related to post-translational modification.

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The US Food and Drug Administration has new guidelines that enable some gene and cell therapies to undergo expedited review, according to the New York Times.

Using gene drives to control invasive species might be too risky, an initial advocate of the approach says.

Researchers have grown tumors in 3D cell cultures to better understand cancer, the Economist reports.

In Science this week: intellectual property experts argue patent battles such as the one over CRISPR are wasteful, and more.