This Week in PLOS

In PLOS Genetics, Yale researchers describe germline and somatic mutations identified in individuals with papillary renal cell carcinoma, a form of kidney cancer that remains difficult to treat. Using exome sequence data for nearly 300 papillary renal cell carcinoma cases, along with whole-genome sequences for 35 more individuals with the disease, the team identified alterations affecting new and known papillary renal cell carcinoma contributors.

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CNN reports that researchers have tied a new variant to opioid addiction risk.

Organoids derived from patients' tumors may help determine what chemotherapy treatment patients would benefit from, according to New Scientist.

An initiative from GenomeAsia 100K hopes to increase the number of South Asians in genetic research, according to NBC News.

In Science this week: genomic analysis of ancient and modern horses indicates population turnover, and more.