This Week in PLOS

In PLOS Genetics, researchers from the UK and Denmark describe an apparent role for the lectin complement pathway gene COLEC10 in craniofacial development. The team used targeted and/or exome sequencing to search for suspicious mutations in 45 families affected by Carnevale, Mingarelli, Michels, and Malpuech syndromes — a set of rare, autosomal recessive, developmental conditions that are collectively called 3MC syndrome.

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The US Food and Drug Administration has new guidelines that enable some gene and cell therapies to undergo expedited review, according to the New York Times.

Using gene drives to control invasive species might be too risky, an initial advocate of the approach says.

In Science this week: intellectual property experts argue patent battles such as the one over CRISPR are wasteful, and more.

Researchers have grown tumors in 3D cell cultures to better understand cancer, the Economist reports.