This Week in PLOS

In PLOS Genetics, an international team led by investigators in the UK describes a mitochondrial mutation involved in a progressive kidney disease called tubulointerstitial kidney disease, which can eventually lead to renal failure. In a UK family with a maternally inherited form of the disease, the researchers did mitochondrial genome sequencing on urinary epithelial cells in affected individuals.

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The US Food and Drug Administration has new guidelines that enable some gene and cell therapies to undergo expedited review, according to the New York Times.

Using gene drives to control invasive species might be too risky, an initial advocate of the approach says.

In Science this week: intellectual property experts argue patent battles such as the one over CRISPR are wasteful, and more.

Researchers have grown tumors in 3D cell cultures to better understand cancer, the Economist reports.