This Week in PLoS

Scientists at the University of Edinburgh have found that the DISC1 gene affects how patients with schizophrenia respond to treatment. Their work was published in PLoS One this week. Looking across public datasets, they found correlations between variants in the DISC1 pathway genes and levels of gene expression, and that variants of DISC1, NDE1, PDE4B, and PDE4D regulate the expression of cytoskeletal, synaptogenic, neurodevelopmental, and sensory perception proteins.

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The New York City medical examiner is overseeing an effort to identify missing persons using DNA, according to the Associated Press.

Nobel laureate Günter Blobel has died at 81, the New York Times reports.

In PNAS this week: mouse model of genetically induced emphysema, gene expression signatures of circulating melanoma cells, and more.

Technology Review reports that 2017 was the year of consumer genetic testing and that it could spur new analysis companies.