This Week in PLoS

Scientists at the University of Edinburgh have found that the DISC1 gene affects how patients with schizophrenia respond to treatment. Their work was published in PLoS One this week. Looking across public datasets, they found correlations between variants in the DISC1 pathway genes and levels of gene expression, and that variants of DISC1, NDE1, PDE4B, and PDE4D regulate the expression of cytoskeletal, synaptogenic, neurodevelopmental, and sensory perception proteins.

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The New York Times and ProPublica say that many physicians fail to disclose their financial ties when publishing in medical journals.

The Wall Street Journal reports Human Longevity's valuation has dropped by 80 percent.

Science reports that the US National Cancer Institute is cutting its operating budget by 5 percent.

In PLOS this week: similar variants seen in bullbogs, people with Robinow syndrome; ApoE genotypes in African-American, Puerto Rican populations; and more.