Researchers from the University of North Carolina at Chapel Hill explore genomic structure diversity in mosquito-borne alphaviruses with a method called "selective 2'-hydroxyl acylation analyzed by primer extension and mutational profiling," or SHAPE-MaP. The team focused on the Sindbis virus and the Venezuelan equine encephalitis virus, using SHAPE-MaP to uncover widespread structural element diversity among alphaviruses.

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