A team from Germany and China outlines updates to the Online Gene Essentiality, or OGEE, in the second version of the database. In addition to fleshing out essential, non-essential, and conditionally essential gene data gleaned from experiments, text mining, and genetic interactions for new species, the researchers have now included information on essential genes in 16 cancer cell line datasets corresponding with nine cancer types.

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Researchers hope to tease out the signature effects that different carcinogens leave on the genome to determine their contributions to disease, Mosaic reports.

The Wall Street Journal looks into the cost of new gene therapies.

An Imperial College London-led team reports that it was able to use a gene drive to control a population of lab mosquitos.

In PNAS this week: genomic effects of silver fox domestication, limited effect of mitochondrial mutations on aging in fruit flies, and more.