An Italian team has characterized the microRNA repertoire in human retinas using deep, small RNA sequencing on retina samples from 16 individuals and two human retinal pigment epithelium/choroid tissue samples. The researchers estimated that the resulting retinal miRNome encompasses some 90 percent of the miRNAs expressed in the retina, including more than four dozen retina-specific miRNA candidates and thousands of isomiRs, or miRNA variants.

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