This Week in Nature

In this week's Nature, an international team of researchers presents a study that examines the role of rare and lower-frequency gene variants in type 2 diabetes, finding that these genetic variations do not substantially contribute to disease risk. The investigators sequenced whole genomes from about 2,700 people, as well as the exomes of about 13,000 individuals from five ancestry groups, both with and without type 2 diabetes. They also analyzed an additional 112,000 with targeted genotyping.

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