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This Week in Nature: Nov 20, 2014

In Nature this week, researchers from the Mouse ENCODE Consortium publish several papers describing potentially functional elements in the mouse genome, helping to validate the animal as a model organism for human disease, and providing a new resource for the study of mammalian biology. The papers specifically report on DNA elements in the mouse genome, the conservation of trans-acting circuitry during mammalian regulatory evolution, the principles of regulatory information conservation between mouse and human, and topologically associating domains as stable units of replication-timing regulation. GenomeWeb has more on these studies here.

Meanwhile, in Nature Biotechnology, a multi-institute team of scientists presents the draft genome of the ferret, which serves as an important model for various human respiratory diseases including influenza. The researchers also characterized the ferret host response to two influenza virus infections and showed distinct signatures in ferret trachea and lung tissues specific to 1918 or 2009 human pandemic flu outbreaks. GenomeWeb also covers the ferret genome here.

Filed under

The Scan

More Boosters for US

Following US Food and Drug Administration authorization, the Centers for Disease Control and Prevention has endorsed booster doses of the Moderna and Johnson & Johnson SARS-CoV-2 vaccines, the Washington Post writes.

From a Pig

A genetically modified pig kidney was transplanted into a human without triggering an immune response, Reuters reports.

For Privacy's Sake

Wired reports that more US states are passing genetic privacy laws.

Science Paper on How Poaching Drove Evolution in African Elephants

In Science this week: poaching has led to the rapid evolution of tuskless African elephants.