This Week in Nature

In Nature Genetics this week, researchers from the University of Oxford and GlaxoSmithKline present a population reference graph based on multiple reference genome sequences and catalogs of genetic variation that can improve the accuracy of genome inference. Reconstructing the genomes of new samples as paths through the graph, meanwhile, allows for recombination between different haplotypes and additional variants.

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The US Food and Drug Administration has approved Kite Pharmaceuticals' CAR T-cell therapy for large B-cell lymphomas, the New York Times reports.

Kaiser Health News reports that gene therapies could cost more than a million dollars.

Worcester Polytechnic Institute researchers have received a grant to combine biology and computer science for high school students.

In Nature this week: variants associated with obsessive-compulsive disorder, review of key CRISPR enzymes, and more.