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In this week's Nature Medicine, an international research team presents a metagenomic analysis of colorectal cancer datasets, uncovering microbiome biomarkers with clinical potential. The work — which covered 969 fecal metagenomes — revealed a greater richness in the gut microbiome of colorectal cancer patients versus controls and uncovered a number of predictive microbiome signatures.

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Bloomberg reports that vaccine developers won't have to conduct large trials of updated vaccines or vaccine boosters aimed at new viral variants.

The SARS-CoV-2 variant uncovered in California may be more transmissible and partially evade vaccine-induced antibody response, the Los Angeles Times reports.

Francis deSouza, the CEO of Illumina, calls for a global SARS-CoV-2 genomics surveillance network, according to the Financial Times.

In PNAS this week: immunotherapy for hard-to-treat breast cancers, effects of oncogenic histone H3K36M mutations, and more.