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This Week in Nature

In Nature Biotechnology this week, a Seoul National University team reports a new CRISPR-based method for assessing the genome-wide target specificity of adenine base editors. The scientists created a modified version of Digenome-seq — an in vitro whole-genome sequencing method for identifying CRISPR-induced double-strand breaks — that could detect adenine base editor off-target sites with a substitution frequency of 0.1 percent or more, they write.

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Researchers trace DNA on a clay pipe found at a former slave site to a population that lives in what is now Sierra Leone, the Washington Post reports.

Two researchers report on their genetic analysis of samples from a shawl thought to belong to a victim of Jack the Ripper, ScienceInsider reports.

Japan is to release rules governing some gene-edited food, according to NHK World.

In PLOS this week: computational strategy for improving gene set analysis testing, miRNAs linked to sleep apnea, and more.