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In Nature this week, a team from the University of California, San Diego publishes a study demonstrating the feasibility of a gene drive in lab mice. The scientists used CRISPR-Cas9 genome editing to promote the inheritance of an engineered allele of the tyrosinase (Tyr) gene and, while unsuccessful in male rodents, were able to boost the rate of inheritance of the Tyr allele in the female animals to as much as 70 percent.

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