This Week in Nature

In this week's Nature Neuroscience, a team of British and Chinese scientists reports on the use of genome-wide association studies to identify existing drugs that may be effective for new indications in psychiatry. By comparing transcriptomes imputed from GWAS data with drug-induced gene expression profiles from the Broad Institute's Connectivity Map cellular signal database, the researchers were able to identify drug candidates for repositioning for seven psychiatric disorders.

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Researchers hope to tease out the signature effects that different carcinogens leave on the genome to determine their contributions to disease, Mosaic reports.

The Wall Street Journal looks into the cost of new gene therapies.

An Imperial College London-led team reports that it was able to use a gene drive to control a population of lab mosquitos.

In PNAS this week: genomic effects of silver fox domestication, limited effect of mitochondrial mutations on aging in fruit flies, and more.