This Week in Nature

In Nature this week, a Cold Spring Harbor Laboratory-led team publishes an improved maize reference genome, which was assembled and annotated using single-molecule real-time sequencing and high-resolution optical mapping. Relative to the previous reference genome, the new assembly features a 52-fold increase in contig length, as well as significant improvements in the assembly of intergenic spaces and centromeres.

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Researchers hope to tease out the signature effects that different carcinogens leave on the genome to determine their contributions to disease, Mosaic reports.

The Wall Street Journal looks into the cost of new gene therapies.

An Imperial College London-led team reports that it was able to use a gene drive to control a population of lab mosquitos.

In PNAS this week: genomic effects of silver fox domestication, limited effect of mitochondrial mutations on aging in fruit flies, and more.