This Week in Nature

In this week's Nature, an international team of researchers reports a new CRISPR/Cas9-based approach for the targeted integration of transgenes in dividing and non-dividing cells, both in vitro and in vivo. The homology-independent targeted integration (HITI) strategy is expected to help advance basic and translational neuroscience research, according to the investigators, who demonstrated its applicability by improving visual function in rats.

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The UK's Nuffield Council on Bioethics says genetically modifying human embryos could be morally permissible, according to the Guardian.

A new Nature Biotechnology paper reports that CRISPR-Cas9 gene editing can lead to large deletions or complex rearrangements that could be pathogenic.

The Wall Street Journal likens a prototype developed by Synthetic Genomics to a "biological fax machine."

In PNAS this week: strategy for reactivating Rett syndrome-linked MECP2, small molecules able to suppress Staphylococcus aureus virulence, and more.