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A UK team takes a look at mutational signatures associated with DNA mismatch repair deficiency in the Caenorhabditis elegans worm model organism and in human tumor samples. The researchers used mutation accumulation assays and genome sequencing to follow the genetic alterations that accumulated in C. elegans worms missing the DNA mismatch repair genes PMS2 and MLH1 and/or the polymerase subunit-coding gene POLE4.

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The New York Times Magazine examines gender discrimination at the Salk Institute.

Science reports that MD Anderson Cancer Center has dismissed three researchers over foreign tie concerns.

A second death in gene therapy trial for type 1 spinal muscular atrophy is under investigation, according to Reuters.

In PLOS this week: antibiotic resistance patterns in Escherichia coli, a dozen genetic loci tied to varicose vein risk, and more.