Researchers from the University of Chicago and Stanford University explore regulatory variation in human induced pluripotent stem cells (iPSC) and cells that undergone differentiation. Using RNA sequence-based expression clues, chromatin accessibility information gleaned from ATAC-seq, and array-based DNA methylation profiling, the team characterized iPSCs established from 58 Yoruba lymphoblastoid cell lines, along with 14 cardiomyocyte lines differentiated from that iPSC set.

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