Investigators from Albert Einstein College of Medicine and elsewhere describe hydroxymethylation shifts at sites in the pancreatic cancer genome with regulatory roles related to oncogenic processes. Using approaches such as hmC-seal 5'-hydroxymethylation enrichment, bisulfite sequencing, ATAC-seq, and RNA-seq, the team tracked patterns for 5'-hydroxymethylation and cytosine methylation in pancreatic cancer cell lines, patient-derived xenograft tumors, and cancer-free pancreatic samples.

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Mice in New York harbor both antibiotic-resistant bacteria and novel viruses, according to a new analysis of their fecal microbiomes.

Human Heredity and Health in Africa Initiative has issued guidelines for genomic research in the region, according to Nature News.

The Associated Press reports that an ethicist predicts that prenatal diagnosis and other advances will lead to more choices being available to prospective parents.

In Genome Biology this week: approach to analyze alternative polyadenylation, algorithm to predict transcriptomic structural variations, and more.