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Investigators from Albert Einstein College of Medicine and elsewhere describe hydroxymethylation shifts at sites in the pancreatic cancer genome with regulatory roles related to oncogenic processes. Using approaches such as hmC-seal 5'-hydroxymethylation enrichment, bisulfite sequencing, ATAC-seq, and RNA-seq, the team tracked patterns for 5'-hydroxymethylation and cytosine methylation in pancreatic cancer cell lines, patient-derived xenograft tumors, and cancer-free pancreatic samples.

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Bloomberg reports that the DNA-for-cash deal reported in Kentucky might be a more widespread scam.

St. Jude Children's Research Hospital scientists have treated infants with X-linked severe combined immunodeficiency using gene therapy in an early phase study.

St. Louis Public Radio reports that some African Americans are turning to DNA ancestry testing to help guide genealogical searches.

In Nature this week: a genomic analysis of the snailfish Pseudoliparis swirei, ancient DNA analysis gives insight into the introduction of farming to England, and more.