Researchers from Canada and the US report on findings from a phenotypic, genomic, and phylogenetic study of Burkholderia cenocepacia isolates collected over time in chronically infected individuals with cystic fibrosis. Using more than 200 sputum samples obtained over two years to two decades from 16 individuals with cystic fibrosis, the team did systematic phenotyping and genotyping — paired with genome sequencing and comparative genomics — to tease out B.

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The UK's Nuffield Council on Bioethics says genetically modifying human embryos could be morally permissible, according to the Guardian.

A new Nature Biotechnology paper reports that CRISPR-Cas9 gene editing can lead to large deletions or complex rearrangements that could be pathogenic.

The Wall Street Journal likens a prototype developed by Synthetic Genomics to a "biological fax machine."

In PNAS this week: strategy for reactivating Rett syndrome-linked MECP2, small molecules able to suppress Staphylococcus aureus virulence, and more.