A German and French team explores features found in Bacillus subtilis bacteria engineered to have minimized genomes — genomes more than one-third smaller than those of wild-type strains. Using a combination of genome sequencing, metabolite and proteome profiling, expression analyses, and physiological assessments, the researchers characterized B. subtilis strains in which large sets of deletions were introduced to reduce the genome size.

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Robert Redfield is floated as the next director of the US Centers for Disease Control and Prevention, the Washington Post reports.

The New York Times writes that the National Institutes of Health's All of Us Research Program is "ambitious" and that some are concerned it might be overly so.

Representative Lamar Smith's criticism of the National Science Foundation has "changed the nature of the conversation," according to ScienceInsider.

In PLOS this week: non-coding RNA function in yeast, transcriptomic profiles of malaria parasites, and more.