Researchers from the UK and the US introduce a tool called TransRate, for assessing the quality of de novo transcriptome assemblies based on the assembly itself and sequenced reads with no reference. The approach assigns a diagnostic quality score for each contig before bringing these together to consider the entire score, the team explains, noting that the approach can detect common artifacts such as base errors, chimeras, structural errors, or incomplete assemblies.

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Jay Shendure and his colleagues have developed a new method to more comprehensively identify human cell types, the NY Times reports.

Researchers in the UK and Japan have shown that infertility in mice with three sex chromosomes can be overcome, according to the Guardian.

China is embracing preimplantation genetic diagnosis, Nature News reports. 

In PLOS this week: host genetic factors associated with cervical neoplasia progression, population patterns for an ancient flowering rainforest plant, and more.