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Rice University and University of Texas researchers present a computational approach for translating noisy or incomplete genotyping profiles produced by single-cell sequencing into inferred tumor phylogenies. The team applied its statistical inference method — known as SiFit — to tease out tumor trees and tumor genetic heterogeneity from synthetic data and from single-cell exome sequences generated for hundreds of tumor and non-tumor cells from two individuals with colorectal cancer.

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The Wall Street Journal reports that Russia's announcement of a coronavirus vaccine approval was met with concern as safety testing has not yet been completed.

New Scientist writes there aren't much data available on the accuracy of the two rapid COVID-19 tests the UK plans to roll out.

In PNAS this week: downstream effect of oncoprotein fusion, epigenetic changes influence tRNAs in colon cancer, and more.

Nature News reports that recent proposed changes to the US National Science Foundation have raised concerns about a shift away from the agency's focus on basic research.