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Rice University and University of Texas researchers present a computational approach for translating noisy or incomplete genotyping profiles produced by single-cell sequencing into inferred tumor phylogenies. The team applied its statistical inference method — known as SiFit — to tease out tumor trees and tumor genetic heterogeneity from synthetic data and from single-cell exome sequences generated for hundreds of tumor and non-tumor cells from two individuals with colorectal cancer.

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A new report offers ways for small, society publishers to transition to Plan S standards, ScienceInsider says.

A gas explosion sparked a fire at a Russian laboratory that stores dangerous pathogens, the Guardian reports.

Researchers turn to protein analysis to examine an ancient rhino sample, reports.

In PNAS this week: C2CD4A gene involved in insulin secretion, chromosome rearrangements in recurring S. aureus infections, and more.