An international team led by investigators in China and the Netherlands uncovers genes with apparent ties to Hirschsprung disease, a congenital condition characterized by altered enteric nervous system progenitor cell activity that leads to bowel obstruction. Through exome sequencing on two dozen individuals with Hirschsprung disease and their parents, the researchers detected 28 de novo mutations affecting 21 genes.

Get the full story

This story is free
for registered users

Registering provides access to this and other free content.

Register now.

Already have an account?
Login Now.

A former Synthetic Genomics attorney alleges that the firm discriminated against her and other female employees, according to the San Diego Union-Tribune.

Due to privacy and lab certification questions, the planned giveaway of Orig3n testing kits at a Baltimore Ravens game was suspended.

Alnylam reports positive results from its phase 3 clinical trial of an RNAi-based drug, according to Stat News.

In Cell this week: adult mesenchymal cell populations in mouse lung, genetic diversity in HPV16 and cancer risk protection, and more.