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Researchers from the Netherlands, the US, and the UK share details about the method they used to establish and start characterizing a biobank of organoids from individuals with colorectal cancer. After developing 22 tumor and 19 matched normal organoids with samples from 20 colorectal cancer patients, they used whole-exome sequencing, array-based gene expression profiling, viability assays, and other approaches to compare features in the organoids with those found in the tissues used to develop them.

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At a meeting this week, researchers and others discussed the regulatory oversight needed for germline genome editing.

The US Food and Drug Administration has asked questions about Myriad Genetics' GeneSight test, according to Bloomberg.

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In Science this week: approach to infer genotype-by-environment interaction from genetic variants associated with phenotypic variability, and more.