This Week in Cell

A team from the UK, Denmark, and US explore the potential consequences that genetic variation might have on response to drugs targeting G-protein-coupled receptors (GPCRs). For their pharmacogenomic analysis, the researchers brought together genetic variation or mutation data representing drug-targeted GPCRs in almost 68,500 individuals from the Exome Aggregation Consortium, 1000 Genomes Project, or parent-child trios from other studies.

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Researchers hope to tease out the signature effects that different carcinogens leave on the genome to determine their contributions to disease, Mosaic reports.

The Wall Street Journal looks into the cost of new gene therapies.

An Imperial College London-led team reports that it was able to use a gene drive to control a population of lab mosquitos.

In PNAS this week: genomic effects of silver fox domestication, limited effect of mitochondrial mutations on aging in fruit flies, and more.