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A Cold Spring Harbor Laboratory-led team describes regulatory changes suspected of contributing to pancreatic cancer. Using organoid cultures developed from paired primary and metastatic pancreatic ductal adenocarcinoma tumors in mouse models, the researchers did mouse re-transplant, RNA sequencing, chromatin immunoprecipitation sequencing, and other experiments to assess genome-wide enhancer patterns as mouse pancreatic tumors progressed.

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A UK woman is suing three National Health Service Trusts for not telling her about her father's Huntington's disease diagnosis, the BBC reports.

LiveScience reports that a novel mutation in the LPL gene was uncovered in three siblings with very high triglyceride levels.

The president of Nankai University is embroiled in a data manipulation scandal, the South China Morning Post reports.

In PNAS this week: cytotoxic CD4 T cell signature in supercentenarians, evolutionary history of beetles, and more.