This Week in Cell

A Massachusetts Institute of Technology-led team catalog essential genes in more than a dozen human acute myeloid leukemia (AML) cell lines. With the help of genome-wide CRISPR-based screening, the researchers tallied gene essentiality in 14 AML lines, defining essential genes, genes that were required only in the lines with mutant Ras oncogene activity, and genes with overlapping biological functions that could not be inactivated at the same time.

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The Seattle Times writes that pharmacogenomics testing can help choose medications that may work best for people with depression.

Researchers report that deleting one gene from butterflies affects their wing coloration patterns, according to the Washington Post.

In PNAS this week: genome sequencing of weevil symbionts, retinoid X receptor deletion in lung cancer metastasis, and more.

Sequencing could help combat foodborne illnesses, according to a blog post by Food and Drug Administration officials.