This Week in Cell

A team from the University of California, San Francisco, Stanford University, and elsewhere tallies up essential genes in the bacterial species Bacillus subtilis using a CRISPR/Cas9 interference strategy. After establishing a knockdown library targeting nearly 300 genes that are known or suspected of being essential in the bug, the researchers used CRISPR-based interference to verify essential genes, uncover potential drug targets, and gauge gene interactions and functions.

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A new report highlights the potential threats posed by advances in synthetic biology, NPR reports.

A Bloomberg reporter tried to get her genetic data deleted, but found it's not so simple to do.

Johns Hopkins University's Steven Salzberg and his colleagues have come up with a new estimate for the number of human genes, Nature News reports.

In Genome Research this week: study of intra-tumor heterogeneity, workflow resources for EPIGEN-Brazil, and more.