This Week in Cell

Protein isoforms generated through alternative splicing don't always interact with the same targets, as researchers from the Dana-Farber Cancer Institute report in Cell. Marc Vidal and his colleagues cloned full-length open reading frames of alternatively spliced transcripts for nearly 1,500 human genes. Then, using protein-protein interaction profiling, they compared the pairs to find that they only shared about half their targets.

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The Seattle Times writes that pharmacogenomics testing can help choose medications that may work best for people with depression.

Researchers report that deleting one gene from butterflies affects their wing coloration patterns, according to the Washington Post.

In PNAS this week: genome sequencing of weevil symbionts, retinoid X receptor deletion in lung cancer metastasis, and more.

Sequencing could help combat foodborne illnesses, according to a blog post by Food and Drug Administration officials.