Michelle Lee, the director of the United States Patent and Trademark Office, has resigned, IP Watchdog reports. It adds that she submitted a letter of resignation with apparently immediate effect.

In a note to her staff, Lee wrote that "[i]t has been a tremendous honor to serve our country for the past several years."

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The US Food and Drug Administration has approved Kite Pharmaceuticals' CAR T-cell therapy for large B-cell lymphomas, the New York Times reports.

Kaiser Health News reports that gene therapies could cost more than a million dollars.

Worcester Polytechnic Institute researchers have received a grant to combine biology and computer science for high school students.

In Nature this week: variants associated with obsessive-compulsive disorder, review of key CRISPR enzymes, and more.