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Team Tracks Baltic Herring Population Patterns With Ancient, Modern DNA Sequences

For a paper appearing in PNAS this week, a team at the University of Oslo, Nicolaus Copernicus University, and other European centers retrace population patterns for herring in the Baltic Sea, where the fish trade appears to go back to the Viking Age. Using new and published whole-genome sequencing, the researchers assessed genome-wide sequence patterns in 40 ancient herring samples going back nearly 1,300 years from sites in Denmark, Poland, or Estonia and 68 representatives from present-day herring populations in the Baltic or Atlantic regions, following the demographic changes, genomic shifts, and adaptations that accompanied environmental changes and more intense fishery-related pressures. "Our results illustrate the importance of including knowledge regarding long-term population dynamics, including differential stock responses to climate change, in sustainable management strategies, as efforts to achieve food security by aquaculture- and marine-based industries are demanding ever-increasing resources from the oceans," the authors write.

The Scan

Open Pediatric Brain Tumor Atlas Team Introduces Genomic Data Collection, Analytical Tools

A study in Cell Genomics outlines open-source methods being used to analyze and translate whole-genome, exome, and RNA sequence data from the Pediatric Brain Tumor Atlas.

Neurological Outcomes Linked to Innate Immune Features After Cardiac Arrest

Researchers reporting in Med dig into immune features found a few hours after cardiac arrest that correspond with neurological outcomes.

Mouse Study Finds Circadian Rhythm-Related Gene Expression Changes Linked to Sleep Apnea

A paper in PLOS Biology reveals tissue-specific circadian rhythm and gene expression patterns in an intermittent hypoxia-based mouse model of obstructive sleep apnea.

Polygenic Risk Score to Predict Preeclampsia, Gestational Hypertension in Pregnant Women

Researchers in Nature Medicine provide new mechanistic insights into the development of hypertensive disorders of pregnancy, which may help develop therapeutics.