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Some, Not All Results

A number of US research institutions have been slow to report their clinical trial findings, Nature News reports.

It notes that federal law requires clinical trials in the US to be registered at and for most trials to report their results there within a year. But, according to a report compiled by Universities Allied for Essential Medicines and TranspariMed using data from the FDA Amendments Act TrialsTracker, 15 of the 40 institutions examined were in full compliance. Institutions in full compliance include Duke University, Yale University, and Washington University, among others, it says.

However, results from 140 trials conducted by the institutions analyzed are not included on the registry, and five institutions — the University of California, San Francisco, Columbia University, the Mayo Clinic, MD Anderson Cancer Center, and the University of Chicago — account for half of those unreported trials, the report says. Spokespeople from UCSF and Columbia tell Nature News that some of the trials included on the list are still ongoing, the data are being analyzed, or the data have been submitted to the registry but don't yet appear there.

The Scan

Alzheimer's Risk Gene Among Women

CNN reports that researchers have found that variants in MGMT contribute to Alzheimer's disease risk among women but not men.

Still Hanging Around

The Guardian writes that persistent pockets of SARS-CoV-2 in the body could contribute to long COVID.

Through a Little Spit

Enteric viruses like norovirus may also be transmitted through saliva, not just the fecal-oral route, according to New Scientist.

Nature Papers Present Method to Detect Full Transcriptome, Viruses Infecting Asgard Archaea, More

In Nature this week: VASA-seq approach to detect full transcriptome, analysis of viruses infecting Asgard archaea, and more.