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Some Big Trees

The San Francisco Chronicle reports that researchers have sequenced the genomes of both the coast redwood and the giant sequoia. It adds that having the trees' genomes may enable researchers to figure out ways to protect them from the effects of climate change.

According to the University of California, Davis, the coast redwood genome is the second-largest genome ever sequenced at a size of 27 billion basepairs, which it notes is nine times the size of the human genome, which is about 3 billion basepairs. The giant sequoia genome, meanwhile, is about three times the size of the human genome, it adds. The researchers, who are from UC Davis, Johns Hopkins University, and the Save the Redwoods League, have made their data publicly available.

"Now we can screen for genetic diversity and make restoration decisions," Emily Burns, the director of science for Save the Redwoods League, tells the Chronicle. "We want to know which genes are influential for drought tolerance and fire resistance. It's the road map for how we are going to conserve the species in the future."

The Scan

And a Fourth?

A fourth dose of the Pfizer-BioNTech SARS-CoV-2 vaccine in an Israeli study increased antibody levels but did not prevent Omicron variant infections, according to the Financial Times.

For Better Science Software

A virtual institute funded by former Google CEO Eric Schmidt's philanthropy aims to lure software engineers to academia, Science reports.

Recommendation Explanations

The New York Times writes that the US Centers for Disease Control and Prevention is straining to both make and explain decisions based on limited information.

Genome Research Papers on De Novo Mutation Rates, Polyploid Genotyping, Oncogene Epigenomic Translocation

In Genome Research this week: de novo mutations rates in hemoglobin subunits, analysis of variant calling methods for polyploid plants, and more.