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About two meters' worth of DNA is crammed into a nucleus that's only some five micrometers to 10 micrometers wide, and though how it's arranged in there influences gene expression, Science News' Sarah Schwartz writes that researchers have only recently been able to begin to tease apart genomic architecture and how it shifts over time.

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Matt Hancock, the UK health secretary, is calling for the swift rollout of predictive genetic tests, the Guardian reports.

A WHO panel is calling for a global registry of human germline gene-editing projects, according to Stat News.

Vox writes that lab mishaps involving pathogens are quite common.

In Genome Biology this week: analysis of wild and cultivated peach genomes, Hi-C-based pipeline for assembling microbial genomes from metagenomic data, and more.