Smushed In

About two meters' worth of DNA is crammed into a nucleus that's only some five micrometers to 10 micrometers wide, and though how it's arranged in there influences gene expression, Science News' Sarah Schwartz writes that researchers have only recently been able to begin to tease apart genomic architecture and how it shifts over time.

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The US National Institutes of Health and the Food and Drug Administration have proposed changing gene therapy oversight, the Associated Press reports.

Nature News reports that the Salk Institute has asked for the scope of a gender discrimination lawsuit brought against it to be narrowed.

CNBC reports that the sequencing startup Veritas aims to sequence individuals who fall at extremes.

In PLOS this week: genotyping of indigenous North African goats, program to simulate evolve and resequencing studies, and more.