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Seems to Support

Regulators at the US Food and Drug Administration seem to have a favorable view of Biogen's Alzheimer's disease therapy, Stat News reports

In early studies, aducanumab seemed to lead to a decline in the amount of amyloid protein that accumulates in Alzheimer's disease patients' brains as well as limit cognitive decline. But trial data led the company to conclude the drug was not working as hoped and it terminated its studies. However, in 2019, the company resurrected the drug, as Time magazine then reported. In particular, the Wall Street Journal reported that it appeared that patients with a certain ApoE variant given a high dose of the drug experienced less cognitive decline.

According to Stat News, FDA officials seem to support Biogen's assessment of its trial data that the drug is helpful to patients. "[T]he applicant has provided substantial evidence of effectiveness to support approval," the agency wrote in a recently released document.

Stat News adds that a panel of outside advisors to FDA are to meet Friday to discuss whether to recommend aducanumab for approval. CNBC adds that the agency's final decision on the drug is expected by March.

The Scan

For Privacy's Sake

Wired reports that more US states are passing genetic privacy laws.

Science Paper on How Poaching Drove Evolution in African Elephants

In Science this week: poaching has led to the rapid evolution of tuskless African elephants.

Guidelines for Ancient DNA Work

More than two dozen researchers have developed new ethical guidelines for conducting ancient DNA research, which they present in Nature.

And Cleared

A UK regulator has cleared former UK Prime Minister David Cameron in concerns he should have registered as a consultant-lobbyist for his work with Illumina, according to the Financial Times.