Skip to main content
Premium Trial:

Request an Annual Quote

Second One From Kite

The US Food and Drug Administration has approved a second gene therapy, this one from Kite Pharmaceuticals, the New York Times reports. The agency approved Novartis' Kymriah earlier this year.

Kite's Yescarta, a CAR T-cell therapy in which patients' own T cells are removed and genetically engineered, has been given the OK to treat adults with certain types of large B-cell lymphoma who have not responded or relapsed after two rounds treatment. Patients would receive a single treatment, Fortune notes.

In a clinical trial of more than a hundred patients with diffuse large B-cell lymphoma, primary mediastinal B-cell lymphoma, or transformed follicular lymphoma, 54 percent of patients experienced complete remission, while 28 percent had partial remissions, according to the Times. It adds that after six months, 80 percent of the patients were still alive and after nine months, 39 percent were still in complete remission.

"Many patients were seriously contemplating their own mortality," Dana-Farber Cancer Institute's Caron Jacobson, who was part of the study, tells the paper.

According to Fortune, Kite, which is part of Gilead Sciences, has set the list price for Yescarta at $373,000.

The company hopes that in the future that Yescarta will be approved for earlier stages of lymphoma as well, the Times adds.

The Scan

More Boosters for US

Following US Food and Drug Administration authorization, the Centers for Disease Control and Prevention has endorsed booster doses of the Moderna and Johnson & Johnson SARS-CoV-2 vaccines, the Washington Post writes.

From a Pig

A genetically modified pig kidney was transplanted into a human without triggering an immune response, Reuters reports.

For Privacy's Sake

Wired reports that more US states are passing genetic privacy laws.

Science Paper on How Poaching Drove Evolution in African Elephants

In Science this week: poaching has led to the rapid evolution of tuskless African elephants.