Science Papers on Human Minor Spliceosome, SARS-CoV-2 Data Enables Key Analyses

Jan 29, 2021

The atomic structure of the activated human minor spliceosome is reported in Science this week. The minor spliceosome is responsible for splicing a rare but essential intron type known as U12-type introns. Its existence has been known for decades, yet relatively little is known about its composition, functional states, catalysis, and regulation due to its scarcity.

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