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Using a combination of transcriptomic, imaging, and genetic lineage labeling methods, a University of Oxford team has mapped the origin of the embryonic mouse heart at single-cell resolution. As reported in this week's Science, the scientists micro-dissected a portion of the embryonic mouse heart to collect cells involved in the formation of the cardiac crescent that subsequently transform into the linear heart tube.

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Moderna reports its vaccine is effective against new SARS-CoV-2 strains, though it is also developing a booster, according to the New York Times.

A new analysis suggests the B.1.1.7 strain of SARS-CoV-2 could be deadlier than previous ones, according to the Guardian.

NPR reports Merck is halting the development of its two candidate SARS-CoV-2 vaccines following disappointing Phase 1 results.

In PLOS this week: gene mutation linked to inherited venous thrombosis, lncRNA patterns in the Asian tiger mosquito, and more.