Close Menu

A team of researchers from Massachusetts General Hospital have developed a new Cas9 variant that virtually eliminates the reliance on protospacer adjacent motifs (PAM) in CRISPR-based genome editing. The recognition of PAM sequences by Cas enzymes is required for successful cleavage of target DNA in CRISPR systems, but constrains targeting and affects editing efficiency and flexibility.

To read the full story....

...and receive Daily News bulletins.

Already have a GenomeWeb or 360Dx account?
Login Now.

Don't have a GenomeWeb or 360Dx account?
Register for Free.

An Associated Press report says China refrained from releasing the SARS-CoV-2 genome for more than a week in January, frustrating the World Health Organization.

The Lancet and the New England Journal of Medicine have issued expressions of concern regarding the data used in two COVID-19 papers, the New York Times reports. 

Researchers have sequenced the genome of the mayfly, garnering insight into how insects evolved wings, Science reports.

In Genome Research this week: gene expression in primate brain regions, inversions and breakpoint inverted repeats in the human genome, and more.